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Detectability of perfusion defect in five-dimensional gated-dynamic cardiac SPECT images

Xiaofeng Niu, Yongyi Yang, Michael A. King, and Miles N. Wernick
Purpose: In previous work, the authors developed and demonstrated the concept of an image reconstruction procedure aimed to unify gated and dynamic nuclear cardiac imaging, which the authors have termed five-dimensional (5D) SPECT. Gated imaging permits the clinician to evaluate wall motion and, th ... [Med. Phys. 37, 5102 (2010)] published Tue Aug 31, 2010.

Compressed sensing based cone-beam computed tomography reconstruction with a first-order method

Kihwan Choi, Jing Wang, Lei Zhu, Tae-Suk Suh, Stephen Boyd et al.
Purpose: This article considers the problem of reconstructing cone-beam computed tomography (CBCT) images from a set of undersampled and potentially noisy projection measurements. Methods: The authors cast the reconstruction as a compressed sensing problem based on [script-l] norm minimization con ... [Med. Phys. 37, 5113 (2010)] published Tue Aug 31, 2010.

Assessment of normal tissue complications following prostate cancer irradiation: Comparison of radiation treatment modalities using NTCP models

Rungdham Takam, Eva Bezak, Eric E. Yeoh, and Loredana Marcu
Purpose: Normal tissue complication probability (NTCP) of the rectum, bladder, urethra, and femoral heads following several techniques for radiation treatment of prostate cancer were evaluated applying the relative seriality and Lyman models. Methods: Model parameters from literature were used in ... [Med. Phys. 37, 5126 (2010)] published Tue Aug 31, 2010.

Improved accuracy of cortical bone mineralization measured by polychromatic microcomputed tomography using a novel high mineral density composite calibration phantom

Justin M. Deuerling, David J. Rudy, Glen L. Niebur, and Ryan K. Roeder
Purpose: Microcomputed tomography (micro-CT) is increasingly used as a nondestructive alternative to ashing for measuring bone mineral content. Phantoms are utilized to calibrate the measured x-ray attenuation to discrete levels of mineral density, typically including levels up to 1000 mg HA/cm, w ... [Med. Phys. 37, 5138 (2010)] published Tue Aug 31, 2010.

Comment on Monte Carlo dosimetry of Co HDR brachytherapy sources [Med. Phys. 30, 712721 (2003)]

T. Palani Selvam, Sridhar Sahoo, and R. S. Vishwakarma
Abstract not available. [Med. Phys. 37, 5146 (2010)] published Tue Aug 31, 2010.

What's New

Fifty-Sixth Annual Meeting of the Canadian Organization of Medical Physicists and the Canadian College of Physicists in Medicine

The meeting abstracts begin on p. 3384 of the July issue.

American Association of Physicists in Medicine 52nd Annual Meeting and Technical Exhibition

This year's Annual Meeting emphasizes the topic of patient safety. The meeting abstracts begin on p. 3019 of the June issue.

50th Anniversary Papers

An Online Compilation of AAPM 50th anniversary papers published in Medical Physics. Click here for the free pdf. Click here for a table of contents of these papers.

Editor's Picks

p4011_fig5

Hybrid x-ray/optical luminescence imaging: Characterization of experimental conditions

C. M. Carpenter, C. Sun, G. Pratx, L. Xing, and R. Rao

Purpose: The feasibility of x-ray luminescence imaging is investigated using a dual-modality imaging system that merges x-ray and optical imaging. This modality utilizes x-ray activated nanophosphors that luminesce when excited by ionizing photons. By doping phosphors with lanthanides, which emit light in the visible and near infrared range, the luminescence is suitable for biological applications. This study examines practical aspects of this new modality including phosphor concentration, light emission linearity, detector damage, and spectral emission characteristics. Finally, the contrast produced by these phosphors is compared to that of x-ray fluoroscopy.

Med. Phys. 37, 4011 (2010)

p4445_fig1

Measurement and verification of positron emitter nuclei generated at each treatment site by target nuclear fragment reactions in proton therapy

Aya Miyatake, Teiji Nishio,Takashi Ogino, Nagahiro Saijo, Hiroyasu Esumi, and Mitsuru Uesaka

Purpose: The purpose of this study is to verify the characteristics of the positron emitter nuclei generated at each treatment site by proton irradiation.

Med. Phys. 37, 4445 (2010)

p4193_fig5

Thermoacoustic molecular tomography with magnetic nanoparticle contrast agents for targeted tumor detection

Liming Nie, Zhongmin Ou, Sihua Yang, and Da Xing

Purpose: The primary feasibility steps of demonstrating the ability of microwave-induced thermoacoustic (TA) in phantoms have been previously reported. However, none were shown to target a diseased site in living subjects in thermoacoustic tomography (TAT) field so far. To determine the expressions of oncogenic surface molecules, it is quite necessary to image tumor lesions and acquire pathogenic status on them via TAT.

Med. Phys. 37, 4193 (2010)


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